Building Endurance in your company is a function of Mission, Vision, Values and Leadership. It is easier to define when you are in the Startup stage but very difficult to keep focus on. Large companies fall because they take their focus away from it.
Founders doing things to change the world for the better. Example here is Billions in Change by Manoj Bhargava, the founder of 5 hour energy. He is investing in technology to solve 3 large problems, Water, Energy and Health.